The MKMRF are delighted to announce the recipient of this years £100,00 Award is Dr SamJanes, Senior Lecturer and Honorary Consultant at University College London.
Research Study:
Treating Malignant Mesothelioma with Stem Cells
Despite major advances in several cancers over the past thirty years mesothelioma is still incurable and all those affected will die of the disease.
Dr Janes has recently demonstrated that Mesenchymal Stem Cells (MSC) usually found in bone marrow preferentially travel to and integrate into tumours where they form some of the infrastructure called stoma. He has shown in a mestastic lung cancer that these cells can deliver a therapy to the tumour cells that result in the death of tumour cells but not the normal surrounding tissue cells.
He now wants to deliver this therapy to Mesothelioma. Using this system in another tumour initial experiments to control the growth of tumours has in almost 40% of cases eliminate them. If successful this may introduce a new era of treatments for Mesothelioma patients.
Mesothelioma is particularly suitable to this type of therapy because the cells can be delivered by a tube directly into the chest avoiding problems encountered in trying to target other cancer cells around the body.
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