The Bart's laboratory programme is aiming to understand the biology of malignant mesothelioma.
The main interests of our laboratory group are:
- The study of apoptotic mechanisms and sites of drug resistance in malignant mesothelioma.
With the use of tissue and molecular biology techniques, we are trying to identify dysfunctional proteins in the mesothelioma apoptotic pathway and sites of drug resistance.
The protein identified might be novel targets for effective treatment.
The genetics of malignant pleural mesothelioma.
Mesothelioma cell-line studies and state of the art genomic array technology is used to identify alterations in the mesothelioma genome and provide information for target therapy.
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